One fascinating thing I’d like to point out: Dr. Shoemaker has often said that it’s about 25% of the population is susceptible to biotoxin-associated illness. When you add up who’s been diagnosed with a psychiatric illness, it too adds up to about 25% of the population. Is that a coincidence? Perhaps. But it’s a very interesting coincidence to me.
One of the goals of Indoor Environmental Professionals is to help people gain knowledge about mold and indoor air quality issues.

We are accomplishing this goal with our community, networking efforts, and our website.

One of the health concerns with winter is the issue of Seasonal Affective Disorder (SAD) which is common because of a lack of sun light. One of the symptoms is depression.

Are you aware that mold is another potential cause of depression?





According to WebMD, depression symptoms include the following:

  • Difficulty concentrating, remembering details, and making decisions;
  • Fatigue and decreased energy;
  • Feelings of guilt, worthlessness, and/or helplessness;
  • Feelings of hopelessness and/or pessimism;
  • Insomnia, early morning wakefulness, or excessive sleeping;
  • Irritability, restlessness;
  • Loss of interest in activities or hobbies once pleasurable, including sex;
  • Loss of pleasure in life;
  • Overeating or appetite loss;
  • Persistent aches or pains, headaches, cramps, or digestive problems that do not ease even with treatment;
  • Persistent sad, anxious, or “empty” feelings;
  • Thoughts of suicide or suicide attempts

Not surprisingly, many symptoms of depression are also associated with Chronic Inflammatory Syndrome (CIRS), Fatigue, Weakness, Aches, Muscle Cramps, Unusual Pain, Ice Pick Pain, Headache, Light Sensitivity, Red Eyes, Blurred Vision, Tearing, Sinus Problems, Cough, Shortness of Breath, Abdominal Pain, Diarrhea, Joint Pain, Morning Stiffness, Memory Issues, Focus/Concentration Issues, Word Recollection Issues, Decreased Learning of New Knowledge, Confusion, Disorientation, Skin Sensitivity, Mood Swings, Appetite Swings, Sweats (especially night sweats), Temperature Regulation or Dysregulation Problems, Excessive Thirst, Increased Urination, Static Shocks, Numbness, Tingling, Vertigo, Metallic Taste, and Tremors.




In 2007, researchers at Brown University released a study showing a link between mold and depression.

The study, led by epidemiologist Edmond Shenassa, analyzed data from 5,882 adults in 2,982 households.

The data was collected by the World Health Organization in 2002 and 2003. Interviewers visited 1000s of homes in eight European cities and asked residents a series of questions to assess symptoms of depression, including symptoms of low appetite, self-esteem, and sleep disturbances. What they found was that symptoms of depression were up to 40% higher for residents living in visibly moldy households than for residents that did not have mold in their homes.

Based on this survey, they concluded that there is a definite connection between damp, moldy homes and depression.

Further concluded that:


Physical health, and perceptions of control, are linked with an elevated risk for depression, and that makes sense. If you are sick from mold, and feel you can’t get rid of it, it may affect your mental health. Healthy homes promote healthy lives.




On the surface, it would appear that the Brown study is anecdotal because it failed to take actual tests of the mold to verify the species and spore count. This is one of the biggest criticisms of the study. That being said, this study does show a link between the home’s environment and the mental health of the occupants.

To further demonstrate the link between mold and depression, one can also look at actual testimonials of individuals that have suffered from mold illnesses. In 2015, Wonder Makers Environmental, a Michigan based environmental company, launched a website,, dedicated to educating restoration contractors, physicians, and patients about mold. One of the goals of the website was to interview toxic mold survivors and record their answers to a series of questions.

One of the common themes in each interview was the sense of hopelessness and depression that they all felt because of the chronic exposure to the mold. Mold does affect one’s brain and continued exposure to mold contributes to symptoms of depression. These are some of the symptoms reported by survivors, whose brains were impacted:

“My ears were ringing and it felt as if my head was about to explode.”

“I had anxiety, brain fog, memory and cognition problems, difficult concentrating and speaking.”

“I developed chronic headaches and migraines, fatigue, muscle weakness, dizziness, memory issues, and mood swings.”

“I had blurry vision, insomnia, rage, anxiety, panic attacks, ringing ears, twitching muscles, hallucinations, dizzinesss, and nightmares.”

“The first symptom that alerted me that something was wrong was the sensation of crawling on my skin along with ice pick/pinprick pain in random places. Shortly after, I noticed that I had the inability to recollect words, slurry speech, memory loss, and an overwhelming fatigue. Other symptoms included vision disturbances, irritability and severe depression.

“I had burning eyes, headaches, pain in my arms and legs, balance issues, impaired cognitive abilities, and vision issues.”




The Brown University study cited earlier was released in 2007 and was viewed as relatively anecdotal at the time of it’s release because it was based on a question and answer survey and then visual clues of mold, meaning the conclusions were based upon some subjective judgement. Since then, there has been further scientific study to show the link between mold and depression.

The simplest explanation of how mold affects the brain is as follows:
– Toxins released by mold, mycotoxins, can pass directly into your brain.
– The mold enters your body when you breathe the spores and even enters your body through the optic nerves and muscles in your eyes.
– When you are exposed to mold it will enter your body through your nose and eyes via your olfactory neurons which directly communicate with your brain.
– Once the mold toxins are in your brain, it causes neuroinflammation and impacts the function of the frontal cortex of the brain which is the pleasure center of the brain that rules emotion, which in turn leads to depression symptoms.



The first step to treatment is determining if you have mold toxicity. One of the tests used to do this is the visual contrast sensitivity test and blood lab test.

Once these tests confirms that you have biotoxin illness, then the drug that many mold survivors have used to begin the detox process is cholestyramine (CSM), which has been shown to reduce symptoms by up to 75%, provided you remove yourself from the toxic environment.

In addition, the detox process can be enhanced with a low carb and low sugar diet and the addition of supplements such as fish oil, magnesium, turmeric, probiotics, and vitamin D.

Disclaimer: The treatment guidelines listed above should only be adopted after first consulting with a physician familiar with biotoxin illness.




With respect to the evidence linking the relationship between mold and depression, it is quite clear that mold does affect the brain. This is confirmed by:
– Scientific research
– Data offered by the Brown University study
– Mold survivors who have come forward and documented their symptoms.
The evidence is growing and our hope is that medical practitioners treating patients with symptoms of depression will begin asking these two questions:
– How healthy is the air quality of your home?
– Does your home have mold?
Awareness is the key. If you or someone you love is suffering from depression, investigate the air quality of your home and find out if there is mold.

Then take the necessary steps to get better by seeking treatment from a physician experienced in bio-toxin illness and contact Indoor Environmental Professionals so that we can professionally remove the mold from your home and restore the fungal ecology to healthy levels.